{"id":47068,"date":"2024-11-07T14:32:31","date_gmt":"2024-11-07T06:32:31","guid":{"rendered":"https:\/\/www.abesmoke.com\/?p=47068"},"modified":"2024-11-07T14:39:31","modified_gmt":"2024-11-07T06:39:31","slug":"dad0a63a57","status":"publish","type":"post","link":"https:\/\/www.abesmoke.com\/en\/a\/47068","title":{"rendered":"Oral film formulations: A new frontier in high-end innovative preparations."},"content":{"rendered":"<div class=\"bpp-post-content\">\n<section title=\"\u6807\u9898\">\n<section>\n<section>\n<section>\n<section class=\"mp_profile_iframe_wrp\"><\/section>\n<h1><\/h1>\n<section title=\"\u6587\u5b57\u5361\u7247\">\n<section>\n<section>\n<section title=\"\u6807\u9898\">\n<section><strong>On the vast stage of healthcare, every technological innovation is accompanied by a profound commitment to human well-being.<\/strong><\/section>\n<section><\/section>\n<\/section>\n<section title=\"\u6b63\u6587\u7ec4\">\n<section>\n<section title=\"\"><span style=\"font-size: 16px;\">Traditional methods of drug administration, though tried and tested over the years, are increasingly revealing their limitations in modern society: patients who struggle to swallow face frustration with capsules and tablets, children and the elderly often grapple with issues of memory that lead to missed or incorrect dosages, and there is a growing demand for convenience and immediacy in medication delivery.<\/span><span style=\"font-size: 16px;\">Amidst this backdrop, oral thin film technology emerges like a refreshing breeze, ushering in a quiet revolution in the pharmaceutical field.<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section title=\"\">\n<section><\/section>\n<p><span style=\"font-size: 16px;\">Oral dissolvable films, this innovative form of drug delivery, has completely transformed our traditional understanding of \u201ctaking medication.\u201d It discards the cumbersome need for water, eliminates dependence on the digestive system, and seamlessly integrates into our lives with an unprecedented lightness.<\/span><\/p>\n<p><span style=\"font-size: 16px;\">\u00a0<\/span><\/p>\n<p><span style=\"font-size: 16px;\">Imagine this: with just a gentle application, the medication swiftly dissolves in the mouth, crossing the mucosal barrier to reach the bloodstream. This not only significantly enhances delivery efficiency but also provides unprecedented convenience and safety for a wide range of patients, particularly vulnerable populations such as children, the elderly, and those with swallowing difficulties.<\/span><\/p>\n<p style=\"text-align: left;\"><strong style=\"color: #0052ff; letter-spacing: 0.578px;\">\u4e00\u3001\u4ec0\u4e48\u662f\u53e3\u819c\uff1f<\/strong><\/p>\n<\/section>\n<section title=\"\"><span style=\"font-size: 16px; letter-spacing: 0.034em;\">\u00a0<\/span><span style=\"font-size: 16px; letter-spacing: 0.034em;\">\u53e3\u819c\uff0c\u88ab\u5f62\u8c61\u5730\u79f0\u4e3a\u201c\u53e3\u8154\u91cc\u7684\u90ae\u7968\u201d\uff0c\u662f\u4e00\u79cd\u5c06\u836f\u7269\u6eb6\u89e3\u6216\u5206\u6563\u5728\u805a\u5408\u7269\u8f7d\u4f53\u4e2d\u5f62\u6210\u7684\u5355\u5c42\u8584\u819c\u4ea7\u54c1\u3002\u53e3\u819c\u5236\u5242\u7684\u4f5c\u7528\u673a\u5236\u4e3b\u8981\u57fa\u4e8e\u53e3\u8154\u9ecf\u819c\u7684\u4e30\u5bcc\u8840\u7ba1\u7f51\u7edc\u548c\u5feb\u901f\u5438\u6536\u80fd\u529b\u3002<\/span><\/p>\n<p><span style=\"font-size: 16px; letter-spacing: 0.034em;\">\u5f53\u836f\u7269\u901a\u8fc7\u53e3\u819c\u7ed9\u836f\u540e\uff0c\u5b83\u80fd\u591f\u76f4\u63a5\u63a5\u89e6\u5230\u9ecf\u819c\u4e0b\u7684\u8840\u7ba1\uff0c\u907f\u514d\u4e86\u7ecf\u8fc7\u80c3\u80a0\u9053\u7684\u6d88\u5316\u548c\u5438\u6536\u8fc7\u7a0b\u3002\u6b64\u5916\uff0c\u53e3\u8154\u9ecf\u819c\u4e0a\u76ae\u7ec6\u80de\u4e4b\u95f4\u7684\u95f4\u9699\u8f83\u5927\uff0c\u6709\u52a9\u4e8e\u836f\u7269\u5206\u5b50\u7684\u6269\u6563\u548c\u6e17\u900f\u3002\u8fd9\u79cd\u7ed9\u836f\u65b9\u5f0f\u8fd8\u80fd\u591f\u51cf\u5c11\u836f\u7269\u5728\u809d\u810f\u4e2d\u7684\u4ee3\u8c22\uff0c\u4ece\u800c\u964d\u4f4e\u836f\u7269\u7684\u6bd2\u6027\u548c\u526f\u4f5c\u7528\u3002<\/span><\/p>\n<\/section>\n<section title=\"\">\n<section>\n<section title=\"\"><span style=\"font-size: 16px;\">2020\u5e74\u7248\u300a\u4e2d\u534e\u4eba\u6c11\u5171\u548c\u56fd\u836f\u5178\u300b\u4e2d\u5c06\u819c\u5242\u5b9a\u4e49\u4e3a\u539f\u6599\u836f\u4e0e\u9002\u5b9c\u7684\u6210\u819c\u6750\u6599\u7ecf\u52a0\u5de5\u5236\u6210\u7684\u819c\u72b6\u5236\u5242\uff0c\u4f9b\u53e3\u670d\u548c\u9ecf\u819c\u7528\u3002<\/span><\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u00a0<\/span><\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u53e3\u8154\u819c\u5242\u6839\u636e\u4f7f\u7528\u548c\u5438\u6536\u4f4d\u7f6e\u4e5f\u53ef\u5206\u4e3a\u53e3\u6eb6\u819c(oral film)\u3001\u53e3\u988a\u819c(buccal film)\u548c\u820c\u4e0b\u819c(sublingual film)[1]\u3002<\/span><\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u00a0<\/span><\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u76ee\u524d\u56fd\u5185\u5916\u5bf9\u53e3\u6eb6\u819c\u7684\u540d\u79f0\u6682\u4e0d\u7edf\u4e00\uff0c\u56fd\u5916\u5e38\u89c1\u7684\u5305\u62ecoral film \u3001oral thinfilm(OTF)\u3001orodispersible films(ODF)\u7b49\uff1b\u56fd\u5185\u5df2\u6279\u51c6\u4e0a\u5e02\u7684\u53e3\u6eb6\u819c\u82f1\u6587\u540d\u901a\u5e38\u4e3aoral solu-ble film\u3002<\/span><\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u00a0<\/span><\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u53e3\u819c\u4e3b\u8981\u5206\u4e3a\u4e09\u79cd\u7c7b\u578b\uff1a\u820c\u4e0b\u819c\u3001\u53e3\u988a\u819c\u548c\u53e3\u6eb6\u819c\u3002\u8fd9\u4e09\u79cd\u53e3\u8154\u819c\u5242\u5728\u836f\u7269\u5438\u6536\u65b9\u9762\u6709\u7740\u672c\u8d28\u7684\u533a\u522b\u3002<\/span><\/section>\n<\/section>\n<p>&nbsp;<\/p>\n<\/section>\n<section title=\"\">\n<section><img decoding=\"async\" class=\"rich_pages wxw-img\" style=\"word-break: break-word; line-height: 1.75; letter-spacing: 0.8px; writing-mode: horizontal-tb; flex-grow: 1; max-width: none !important; width: 100%; visibility: visible !important; height: auto;\" title=\"Oral film formulations: A new frontier in high-end innovative preparations.\" src=\"https:\/\/www.abesmoke.com\/wp-content\/uploads\/2024\/11\/4-1730961152.webp\" alt=\"Oral film formulations: A new frontier in high-end innovative preparations.\" \/><\/section>\n<\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u00a0<\/span><span style=\"font-size: 16px;\">\u5176\u4e2d\uff0c\u820c\u4e0b\u819c\u548c\u53e3\u988a\u819c\u901a\u8fc7\u7279\u5b9a\u7684\u9ecf\u819c\u5438\u6536\uff0c\u80fd\u6709\u6548\u907f\u514d\u836f\u7269\u5728\u80c3\u80a0\u9053\u7684\u964d\u89e3\u53ca\u809d\u810f\u7684\u9996\u8fc7\u6548\u5e94\uff0c\u63d0\u9ad8\u751f\u7269\u5229\u7528\u5ea6\u3002\u800c\u53e3\u6eb6\u819c\u5219\u4e3b\u8981\u901a\u8fc7\u80c3\u80a0\u9053\u5438\u6536\uff0c\u5c5e\u4e8e\u53e3\u670d\u56fa\u4f53\u5236\u5242\u7684\u4e00\u79cd\u3002<\/span><\/section>\n<section title=\"\">\u00a0<\/section>\n<section title=\"\u4e09\u7ea7\u6807\u9898\">\n<section>\n<section>\n<section>\n<h3><span style=\"font-size: 16px;\"><span style=\"font-size: 16px; color: #0052ff;\"><strong>\u4e8c\u3001\u6838\u5fc3\u4f18\u52bf<\/strong><\/span><\/span><\/h3>\n<\/section>\n<section><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section title=\"\"><span style=\"font-size: 16px;\"><strong>1\u3001\u5feb\u901f\u5438\u6536\u4e0e\u751f\u7269\u5229\u7528\u5ea6<\/strong><\/span><span style=\"font-size: 16px;\">\u00a0<\/span><\/p>\n<ul class=\"list-paddingleft-1\" style=\"list-style-type: circle;\">\n<li>\n<section title=\"\"><span style=\"font-size: 16px;\">\u5feb\u901f\u5438\u6536<\/span><\/section>\n<\/li>\n<\/ul>\n<\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u53e3\u819c\u5236\u5242\u901a\u8fc7\u53e3\u8154\u9ecf\u819c\u76f4\u63a5\u8fdb\u5165\u8840\u6db2\u5faa\u73af\uff0c\u907f\u514d\u4e86\u80a0\u9053\u7684\u6d88\u5316\u5438\u6536\u8fc7\u7a0b\u548c\u809d\u810f\u7684\u9996\u8fc7\u6548\u5e94\uff0c\u56e0\u6b64\u836f\u7269\u53ef\u4ee5\u66f4\u8fc5\u901f\u5730\u8fbe\u5230\u6cbb\u7597\u6d53\u5ea6\u3002\u7814\u7a76\u8868\u660e\uff0c\u8bb8\u591a\u836f\u7269\u901a\u8fc7\u53e3\u8154\u9ecf\u819c\u7ed9\u836f\u540e\uff0c\u5176\u8840\u6d46\u5cf0\u6d53\u5ea6(Cmax)\u51fa\u73b0\u7684\u65f6\u95f4\u660e\u663e\u65e9\u4e8e\u4f20\u7edf\u53e3\u670d\u7ed9\u836f\u3002<\/span><span style=\"font-size: 16px;\">\u00a0<\/span><\/section>\n<ul class=\"list-paddingleft-1\" style=\"list-style-type: circle;\">\n<li>\n<section title=\"\"><span style=\"font-size: 16px;\">\u63d0\u9ad8\u751f\u7269\u5229\u7528\u5ea6<\/span><\/section>\n<\/li>\n<\/ul>\n<section title=\"\"><span style=\"font-size: 16px;\">\u7531\u4e8e\u7ed5\u8fc7\u4e86\u80a0\u9053\u548c\u809d\u810f\u7684\u4ee3\u8c22\uff0c\u8bb8\u591a\u836f\u7269\u7684\u751f\u7269\u5229\u7528\u5ea6\u5728\u53e3\u819c\u7ed9\u836f\u65f6\u5f97\u5230\u4e86\u663e\u8457\u63d0\u9ad8\u3002\u4f8b\u5982\uff0c\u4e00\u9879\u9488\u5bf9\u8377\u5c14\u8499\u66ff\u4ee3\u7597\u6cd5\u7684\u7814\u7a76\u6307\u51fa\uff0c\u901a\u8fc7\u988a\u819c\u7ed9\u836f\u7684\u96cc\u4e8c\u9187\u6bd4\u53e3\u670d\u7ed9\u836f\u6709\u66f4\u9ad8\u7684\u751f\u7269\u5229\u7528\u5ea6\u3002\u4ee5\u96cc\u4e8c\u9187\u4e3a\u4f8b\uff0c\u7814\u7a76\u663e\u793a\u5176\u53e3\u819c\u5236\u5242\u7684\u751f\u7269\u5229\u7528\u5ea6\u53ef\u9ad8\u8fbe50%-80%\uff0c\u800c\u53e3\u670d\u9014\u5f84\u7684\u751f\u7269\u5229\u7528\u5ea6\u901a\u5e38\u4f4e\u4e8e10%\u3002<\/span><span style=\"font-size: 16px;\">\u00a0<\/span><\/section>\n<section title=\"\">\n<section><img decoding=\"async\" class=\"rich_pages wxw-img\" style=\"word-break: break-word; line-height: 1.75; letter-spacing: 0.8px; writing-mode: horizontal-tb; flex-grow: 1; max-width: none !important; width: 100%; visibility: visible !important; height: auto; border-width: 1px; border-style: solid;\" title=\"Oral film formulations: A new frontier in high-end innovative preparations.\" src=\"https:\/\/www.abesmoke.com\/wp-content\/uploads\/2024\/11\/7-1730961152.webp\" alt=\"Oral film formulations: A new frontier in high-end innovative preparations.\" \/><\/section>\n<\/section>\n<section title=\"\"><strong><span style=\"font-size: 16px;\">2\u3001\u907f\u514d\u9996\u8fc7\u6548\u5e94<\/span><\/strong><span style=\"font-size: 16px;\">\u00a0<\/span><\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u9996\u8fc7\u6548\u5e94\u6307\u7684\u662f\u836f\u7269\u5728\u901a\u8fc7\u809d\u810f\u4e4b\u524d\u5df2\u7ecf\u88ab\u90e8\u5206\u4ee3\u8c22\uff0c\u5bfc\u81f4\u5b9e\u9645\u8fdb\u5165\u5168\u8eab\u5faa\u73af\u7684\u836f\u7269\u91cf\u51cf\u5c11\u3002\u53e3\u819c\u5236\u5242\u80fd\u591f\u51cf\u5c11\u6216\u907f\u514d\u8fd9\u79cd\u6548\u5e94\uff0c\u4ece\u800c\u63d0\u9ad8\u4e86\u836f\u7269\u7684\u6574\u4f53\u6548\u7387\u3002<\/span><span style=\"font-size: 16px;\">\u00a0<\/span><\/section>\n<section title=\"\"><strong><span style=\"font-size: 16px;\">3\u3001\u4fbf\u4e8e\u4f7f\u7528\uff0c\u63d0\u5347\u4f9d\u4ece\u6027<\/span><\/strong><span style=\"font-size: 16px;\">\u00a0<\/span><span style=\"font-size: 16px;\">\u53e3\u819c\u5236\u5242\u901a\u5e38\u8bbe\u8ba1\u4e3a\u819c\u7247\u6216\u8005\u8d34\u5242\u7b49\u5f62\u5f0f\uff0c\u4f7f\u7528\u65b9\u4fbf\uff0c\u53e3\u819c\u7684\u5373\u7528\u6027\u548c\u65e0\u6c34\u670d\u7528\u7279\u6027\u663e\u8457\u63d0\u5347\u4e86\u60a3\u8005\u7528\u836f\u7684\u4fbf\u5229\u6027\uff0c\u7279\u522b\u662f\u5bf9\u4e8e\u513f\u7ae5\u3001\u8001\u4eba\u53ca\u6709\u541e\u54bd\u56f0\u96be\u7684\u60a3\u8005\u800c\u8a00\u3002<\/span>&nbsp;<\/p>\n<p><span style=\"font-size: 16px;\">\u4f8b\u5982\uff0c\u5b5f\u9c81\u53f8\u7279\u94a0\u53e3\u6eb6\u819c\u662f\u56fd\u5185\u9996\u4e2a\u4e0a\u5e02\u7684\u5b5f\u9c81\u53f8\u7279\u94a0\u53e3\u6eb6\u819c\u5236\u5242\uff0c\u8fd9\u4e00\u65b0\u5242\u578b\u7684\u4e0a\u5e02\uff0c\u7ed9\u54ee\u5598\u60a3\u513f\u63d0\u4f9b\u4e86\u65b0\u7684\u3001\u66f4\u52a0\u4fbf\u6377\u7684\u7528\u836f\u65b9\u5f0f\uff0c\u6709\u6548\u89e3\u51b3\u4e86\u513f\u7ae5\u670d\u836f\u96be\u7684\u95ee\u9898\u3002<\/span><\/p>\n<p>&nbsp;<\/p>\n<\/section>\n<section title=\"\"><strong><span style=\"font-size: 16px;\">4\u3001\u7cbe\u51c6\u5242\u91cf\u4e0e\u51cf\u5c11\u526f\u4f5c\u7528<\/span><\/strong><span style=\"font-size: 16px;\">\u00a0<\/span><span style=\"font-size: 16px;\">\u53e3\u6eb6\u819c\u7684\u751f\u4ea7\u91c7\u7528\u7cbe\u5bc6\u7684\u5236\u9020\u5de5\u827a\uff0c\u786e\u4fdd\u6bcf\u7247\u542b\u6709\u51c6\u786e\u7684\u836f\u7269\u5242\u91cf\uff0c\u51cf\u5c11\u56e0\u60a3\u8005\u81ea\u884c\u5206\u5272\u836f\u7247\u5bfc\u81f4\u7684\u5242\u91cf\u8bef\u5dee\u3002<\/span><span style=\"font-size: 16px;\">\u00a0<\/span><\/p>\n<p><span style=\"font-size: 16px;\">\u8fd9\u5bf9\u4e8e\u9700\u8981\u4e25\u683c\u63a7\u5236\u5242\u91cf\u7684\u836f\u7269\u5c24\u4e3a\u91cd\u8981\uff0c\u6bd4\u59822020\u5e745\u6708\uff0cFDA\u6279\u51c6\u7531\u65e5\u672c\u4f4f\u53cb\u5236\u836f\u7f8e\u56fd\u5b50\u516c\u53f8\uff08SunovionPharmaceuticals Inc\uff09\u5f00\u53d1\u7684\u76d0\u9178\u963f\u6251\u5417\u5561\u820c\u4e0b\u819c\u5242Kynmobi\u4e0a\u5e02\uff0c\u7528\u4e8e\u5e15\u91d1\u68ee\u75c5\u60a3\u8005\u5173\u95ed\u671f\uff08OFF\uff09\u4e8b\u4ef6\u7684\u6025\u6027\u6cbb\u7597\u3002<\/span><\/p>\n<p><span style=\"font-size: 16px;\">\u00a0<\/span><\/p>\n<p><span style=\"font-size: 16px;\">\u4f5c\u4e3a\u7b2c\u4e00\u4e2a\u5feb\u901f\u3001\u6309\u9700\u6cbb\u7597\u5e15\u91d1\u68ee\u75c5OFF\u4e8b\u4ef6\u820c\u4e0b\u7597\u6cd5\u7684Kynmobi\uff0c\u5728\u820c\u4e0b\u5feb\u901f\u6eb6\u89e3\u3001\u6309\u9700\u6cbb\u7597OFF\u4e8b\u4ef6\uff0c15\u5206\u949f\u8d77\u6548\u300130\u5206\u949f\u663e\u8457\u6539\u5584\u75c7\u72b6\uff0c\u6bcf\u5929\u53ef\u4f7f\u7528\u591a\u8fbe5\u6b21\uff0c\u80fd\u5e2e\u52a9\u60a3\u8005\u8fc5\u901f\u6539\u5584\u53d7\u635f\u7684\u8fd0\u52a8\uff0c\u5e76\u6839\u636e\u5177\u4f53\u9700\u6c42\u63a7\u5236\u4ed6\u4eec\u7684\u8fd0\u52a8\u75c7\u72b6\u3002<\/span><\/p>\n<p><span style=\"font-size: 16px;\">\u00a0<\/span><\/p>\n<\/section>\n<section title=\"\">\n<section><img decoding=\"async\" class=\"rich_pages wxw-img\" style=\"word-break: break-word; line-height: 1.75; letter-spacing: 0.8px; writing-mode: horizontal-tb; flex-grow: 1; max-width: none !important; width: 100%; visibility: visible !important; height: auto; border-width: 1px; border-style: solid;\" title=\"Oral film formulations: A new frontier in high-end innovative preparations.\" src=\"https:\/\/www.abesmoke.com\/wp-content\/uploads\/2024\/11\/6-1730961152.webp\" alt=\"Oral film formulations: A new frontier in high-end innovative preparations.\" \/><\/section>\n<section><span style=\"font-size: 16px;\">\u00a0<\/span><\/section>\n<section><strong><span style=\"font-size: 16px;\">5\u3001\u4f7f\u7528\u8303\u56f4\u5e7f\u6cdb<\/span><\/strong><\/section>\n<section><span style=\"font-size: 16px;\">\u00a0<\/span><\/section>\n<\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u53e3\u6eb6\u819c\u6280\u672f\u4e0d\u4ec5\u9650\u4e8e\u5c0f\u5206\u5b50\u836f\u7269\uff0c\u4e5f\u9002\u7528\u4e8e\u80bd\u7c7b\u836f\u7269\u3001\u75ab\u82d7\u7b49\u5927\u5206\u5b50\u7269\u8d28\u7684\u9012\u9001\uff0c\u5c55\u793a\u4e86\u5176\u5728\u591a\u7c7b\u578b\u836f\u7269\u9012\u9001\u4e0a\u7684\u6f5c\u529b\u3002\u4f8b\u5982\uff0c\u6b63\u5728\u7814\u53d1\u4e2d\u7684\u80f0\u5c9b\u7d20\u53e3\u819c\u5236\u5242\uff0c\u65e8\u5728\u4e3a\u7cd6\u5c3f\u75c5\u60a3\u8005\u63d0\u4f9b\u65e0\u9488\u4e14\u4fbf\u6377\u7684\u8840\u7cd6\u63a7\u5236\u65b9\u6848\u3002<\/span><span style=\"font-size: 16px;\">\u00a0<\/span><\/section>\n<section title=\"\"><strong><span style=\"font-size: 16px;\">6\u3001\u521b\u65b0\u6cbb\u7597\u9886\u57df\u7684\u5e94\u7528<\/span><\/strong><span style=\"font-size: 16px;\">\u00a0<\/span><span style=\"font-size: 16px;\">\u53e3\u6eb6\u819c\u6280\u672f\u5728\u7cbe\u795e\u5065\u5eb7\u3001\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u3001\u6fc0\u7d20\u66ff\u4ee3\u6cbb\u7597\u7b49\u9886\u57df\u5c55\u73b0\u51fa\u5de8\u5927\u6f5c\u529b\u3002\u4f8b\u5982\uff0c\u963f\u7acb\u54cc\u5511\u53e3\u6eb6\u819c\u7528\u4e8e\u7cbe\u795e\u5206\u88c2\u75c7\u548c\u53cc\u76f8\u60c5\u611f\u969c\u788d\u7684\u7ef4\u6301\u6cbb\u7597\uff0c\u5176\u5feb\u901f\u6eb6\u89e3\u7279\u6027\u6709\u52a9\u4e8e\u63d0\u9ad8\u60a3\u8005\u5728\u7d27\u6025\u60c5\u51b5\u4e0b\u7684\u6cbb\u7597\u54cd\u5e94\u7387\uff0c\u4ece\u800c\u66f4\u597d\u5730\u63a7\u5236\u75c5\u60c5\u6ce2\u52a8\u3002<\/span><span style=\"font-size: 16px;\">\u00a0<\/span><\/p>\n<p><span style=\"font-size: 16px;\">\u53e6\u5916\uff0c\u7cbe\u795e\u75be\u75c5\u7c7b\u7684\u60a3\u8005\u666e\u904d\u5b58\u5728\u201c\u85cf\u836f\u201d\u548c\u201c\u5410\u836f\u201d\u7684\u4e60\u60ef\uff0c\u60a3\u8005\u81ea\u5df1\u5e76\u4e0d\u8ba4\u4e3a\u81ea\u5df1\u6709\u75be\u75c5\uff0c\u56e0\u6b64\u5bf9\u5403\u836f\u5177\u6709\u672c\u80fd\u7684\u62b5\u6297\u3002\u800c\u53e3\u6eb6\u819c\u5242\u578b\u5374\u53ef\u4ee5\u5f88\u597d\u7684\u89e3\u51b3\u8fd9\u4e00\u95ee\u9898\uff1a\u5728\u53e3\u8154\u5185\u8fc5\u901f\u6eb6\u89e3\uff0c\u5373\u4f7f\u60a3\u8005\u85cf\u836f\uff0c\u4e5f\u65e0\u6cd5\u50cf\u7247\u5242\u548c\u80f6\u56ca\u90a3\u6837\u518d\u6b21\u53d6\u51fa\uff0c\u800c\u50ac\u5410\u4e5f\u65e0\u6cd5\u5f7b\u5e95\u5c06\u836f\u7269\u5410\u51fa\u3002<\/span><\/p>\n<\/section>\n<section title=\"\">\u00a0<\/section>\n<section title=\"\u4e09\u7ea7\u6807\u9898\">\n<section>\n<section>\n<section>\n<h3><span style=\"color: #0052ff;\"><strong><span style=\"font-size: 16px;\">\u4e09\u3001\u5df2\u4e0a\u5e02\u7684\u53e3\u6eb6\u819c\u5242\u4ea7\u54c1\u53ca\u672a\u6765\u5e02\u573a\u9884\u6d4b<\/span><\/strong><\/span><\/h3>\n<\/section>\n<section><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u636e\u836f\u878d\u4e91\u7684\u6570\u636e\u663e\u793a\uff0c\u5168\u7403\u5df2\u6279\u51c6\u4e0a\u5e02\u4e86\u591a\u6b3e\u53e3\u6eb6\u819c\u4ea7\u54c1\u3002\u56fd\u5916\u4e0a\u5e02\u7684\u53e3\u8154\u819c\u5242\uff0c\u9002\u5e94\u75c7\u96c6\u4e2d\u5728\u7cbe\u795e\u3001\u795e\u7ecf\u3001\u9547\u75db\u3001\u7537\u6027\u52c3\u8d77\u529f\u80fd\u969c\u788d\u7b49\u3002<\/span><span style=\"font-size: 16px;\">\u00a0<\/span><span style=\"font-size: 16px;\">FDA\u6279\u51c6\u7684\u53e3\u8154\u819c\u5242\u6d89\u53ca\u9002\u5e94\u75c7\u8f83\u591a\uff0c\u59822010\u5e74FDA\u6279\u51c6\u7684\u53e3\u6eb6\u819c\u5904\u65b9\u836f\u6602\u4e39\u53f8\u743c\uff0c\u53ef\u7528\u4e8e\u9884\u9632\u672f\u540e\u548c\u653e\u7597\u8bf1\u5bfc\u7684\u6076\u5fc3\u548c\u5455\u5410\u4ee5\u53ca\u56e0\u63a5\u53d7\u4e2d\u81f3\u9ad8\u81f4\u5410\u6027\u80bf\u7624\u5316\u7597\u65b9\u6848\u6cbb\u7597\u6240\u5f15\u8d77\u7684\u6076\u5fc3\u548c\u5455\u5410\uff1b2019\u5e74FDA\u6279\u51c6\u3001\u88ab\u6388\u4e88\u201c\u5b64\u513f\u836f\u201d\u7684\u5229\u9c81\u5511\u53e3\u6eb6\u819c\uff0c\u53ef\u7528\u4e8e\u6cbb\u7597\u808c\u840e\u7f29\u6027\u4fa7\u7d22\u786c\u5316\u75c7\uff08ALS\uff09\uff0c\u4fd7\u79f0\u201c\u6e10\u51bb\u4eba\u201d\u75c7\uff0c\u53e6\u5916\u8fd8\u6709\u6c2f\u5df4\u5360\u3001\u916e\u6d1b\u82ac\u7b49[3]\u3002<\/span><span style=\"font-size: 16px;\">\u00a0<\/span><\/p>\n<p><span style=\"font-size: 16px;\">\u53e6\u5916\u8fd8\u6709\u9547\u75db\u7c7b\u7684\u67b8\u6a7c\u9178\u82ac\u592a\u5c3c\u53e3\u8154\u819c(film\/buccal)\u3001\u76d0\u9178\u4e01\u4e19\u8bfa\u5561\u53e3\u8154\u819c(film\/buccal)\uff0c\u7cbe\u795e\u969c\u788d\u7c7b\u76d0\u9178\u4e01\u4e19\u8bfa\u5561\/\u76d0\u9178\u7eb3\u6d1b\u916e\u820c\u4e0b\u819c(film\/sub-lingual)\u7b49\u3002<\/span><\/p>\n<p><span style=\"font-size: 16px;\">\u00a0<\/span><\/p>\n<p><span style=\"font-size: 16px;\">\u6b27\u76df\u6279\u51c6\u4e0a\u5e02\u591a\u4e3a\u53e3\u8154\u5d29\u89e3\u819c\uff0c\u6d3b\u6027\u6210\u5206\u5305\u62ec\u6602\u4e39\u53f8\u743c\u3001\u5229\u57f9\u916e\u3001\u5965\u6c2e\u5e73\u3001\u76d0\u9178\u591a\u5948\u54cc\u9f50\u3001\u67b8\u6a7c\u9178\u897f\u5730\u90a3\u975e\u3001\u4f50\u7c73\u66f2\u5766\u3001\u82ef\u7532\u9178\u5229\u624e\u66f2\u5766\u7b49\uff0c\u5176\u4e2d\u5fb7\u56fd\u7684\u53e3\u8154\u819c\u5242\u53d1\u5c55\u8fc5\u731b\uff0c\u6279\u51c6\u7684\u819c\u5242\u5728\u7cbe\u795e\u795e\u7ecf\u9886\u57df\u8f83\u4e3a\u96c6\u4e2d\uff0c\u4f8b\u5982\u5229\u57f9\u916e\u53e3\u8154\u819c\u5242(orodispersible film)\u3001\u76d0\u9178\u591a\u5948\u54cc\u9f50\u53e3\u8154\u819c\u5242(orodispersible film)\u7b49\u3002<\/span><\/p>\n<p><span style=\"font-size: 16px;\">\u00a0<\/span><\/p>\n<\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u65e5\u672c\u4e5f\u4e0a\u5e02\u4e86\u591a\u6b3e\u53e3\u6eb6\u819c\u4ea7\u54c1\uff0c\u5982\u6cbb\u7597\u7cbe\u795e\u5206\u88c2\u75c7\u7684\u5965\u6c2e\u5e73\uff08Olanzaran\uff09\uff0c\u6cbb\u7597\u52c3\u8d77\u529f\u80fd\u969c\u788d\u7684\u67b8\u6a7c\u9178\u897f\u5730\u90a3\u975e\uff08Xybilun\uff09\uff0c\u6cbb\u7597\u9ad8\u8840\u7cd6\u7684\u4f0f\u683c\u5217\u6ce2\u7cd6\u7b49\u3002\u53e6\u5916\uff0c\u65e5\u672c\u4e0a\u5e02\u7684\u76d0\u9178\u591a\u5948\u54cc\u9f50\u67093\u4e2a\u89c4\u683c(3\u30015\u548c10mg)\uff0c\u4e3b\u8981\u8f85\u6599\u5305\u62ec\u4e09\u6c2f\u8517\u7cd6\u3001\u7f9f\u4e19\u7ea4\u7ef4\u7d20\u3001\u7f9f\u4e19\u7532\u7ea4\u7ef4\u7d20\u3001\u805a\u4e59\u4e8c\u9187 400\u3001L-\u8584\u8377\u9187\u7b49[6]\uff0c\u5176\u4e2d3mg\u548c5mg\u89c4\u683c\u7684\u957f\u77ed\u8fb9\u3001\u539a\u5ea6\u57fa\u672c\u76f8\u540c(\u957f\u8fb920mm\u3001\u77ed\u8fb914mm\u3001\u539a\u5ea670-90\u03bcm)\uff0c\u800c10mg\u89c4\u683c\u7684\u819c\u5242\u7565\u539a(90-110\u03bcm)\u3002<\/span><span style=\"font-size: 16px;\">\u00a0<\/span><\/section>\n<section title=\"\">\n<section><img decoding=\"async\" class=\"rich_pages wxw-img\" style=\"word-break: break-word; line-height: 1.75; letter-spacing: 0.8px; writing-mode: horizontal-tb; flex-grow: 1; max-width: none !important; width: 100%; visibility: visible !important; height: auto; border-width: 1px; border-style: solid;\" title=\"Oral film formulations: A new frontier in high-end innovative preparations.\" src=\"https:\/\/www.abesmoke.com\/wp-content\/uploads\/2024\/11\/8-1730961153.webp\" alt=\"Oral film formulations: A new frontier in high-end innovative preparations.\" \/><\/section>\n<section><\/section>\n<section><span style=\"font-size: 16px;\">\u5fb7\u56fd\u4e0e\u65e5\u672c\u4e0a\u5e02\u7684\u90e8\u5206\u7cbe\u795e\u7c7b\u53e3\u8154\u819c\u5242<br \/>\n<\/span><\/section>\n<p><img decoding=\"async\" class=\"rich_pages wxw-img\" style=\"visibility: visible !important; width: 100%; height: auto; border-width: 1px; border-style: solid;\" title=\"Oral film formulations: A new frontier in high-end innovative preparations.\" src=\"https:\/\/www.abesmoke.com\/wp-content\/uploads\/2024\/11\/3-1730961153.webp\" alt=\"Oral film formulations: A new frontier in high-end innovative preparations.\" \/><\/p>\n<section><\/section>\n<\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u62a5\u544a\u663e\u793a\uff0c\u53e3\u6eb6\u819c\u5242\u5728\u56fd\u5185\u4ece2020\u5e74\u8d77\u53d1\u5c55\u52a0\u901f\uff0c\u83b7\u6279\u54c1\u79cd\u8fbe8\u4e2a\uff0c\u6d89\u53ca\u4f01\u4e1a\u4e3b\u8981\u4e3a\u9f50\u9c81\u5236\u836f\u3001\u6052\u745e\u533b\u836f\u3001\u6c5f\u82cf\u8c6a\u68ee\u53ca\u534e\u6da6\u7d2b\u7af9\u836f\u4e1a\uff0c\u5176\u4e2d\u9f50\u9c81\u5236\u836f\u76f8\u5173\u4e0a\u5e02\u836f\u54c1\u6570\u8fbe5\u4e2a\u3002<\/span><span style=\"font-size: 16px;\">\u00a0<\/span><\/section>\n<section title=\"\">\n<section><img decoding=\"async\" class=\"rich_pages wxw-img\" style=\"word-break: break-word; line-height: 1.75; letter-spacing: 0.8px; writing-mode: horizontal-tb; flex-grow: 1; max-width: none !important; width: 100%; visibility: visible !important; height: auto; border-width: 1px; border-style: solid;\" title=\"Oral film formulations: A new frontier in high-end innovative preparations.\" src=\"https:\/\/www.abesmoke.com\/wp-content\/uploads\/2024\/11\/2-1730961153.webp\" alt=\"Oral film formulations: A new frontier in high-end innovative preparations.\" \/><\/section>\n<\/section>\n<section title=\"\">\n<section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u5176\u4e2d\uff0c\u5965\u6c2e\u5e73\u53e3\u6eb6\u819c\u7528\u4e8e\u6cbb\u7597\u795e\u7ecf\u5206\u88c2\u75c7\uff0c\u4f5c\u7528\u9776\u70b95-HT2\u3001DRD1\u3001DRD2\u3001DRD3\u3001DRD4\u3002\u539f\u7814\u5382\u5546\u4e3a\u793c\u6765\uff0c2000\u5e747\u6708\u5728\u6211\u56fd\u83b7\u6279\u4e0a\u5e02\uff0c\u540e\u6210\u4e3a\u6297\u7cbe\u795e\u5206\u88c2\u75c7\u7684\u4e34\u5e8a\u4e00\u7ebf\u6cbb\u7597\u836f\u7269\u3002<\/span><\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u00a0<\/span><\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u622a\u81f3\u76ee\u524d\uff0c\u51712\u5bb6\u4f01\u4e1a\u83b7\u5f97\u751f\u4ea7\u6279\u6587\uff0c\u5206\u522b\u4e3a\u8c6a\u68ee\u836f\u4e1a\u3001\u9f50\u9c81\u5236\u836f\u3002\u5965\u6c2e\u5e73\u53e3\u6eb6\u819c\u5c5e\u4e8e\u533b\u4fdd\u4e59\u7c7b\u836f\u7269\uff0c\u88ab\u7eb3\u5165\u96c6\u4e2d\u91c7\u8d2d\uff0c\u9f50\u9c81\u5236\u836f\u6210\u529f\u4e2d\u6807\uff0c5mg\u89c4\u683c\u4e2d\u9009\u4ef7\u683c\u4e3a129.67\u5143\u300110mg\u89c4\u683c\u4e2d\u9009\u4ef7\u683c110.22\u5143\uff0c\u964d\u5e45\u5747\u8d85\u8fc766%\u3002<\/span><\/section>\n<\/section>\n<p>&nbsp;<\/p>\n<section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u62a5\u544a\u663e\u793a\uff0c\u5965\u6c2e\u5e73\u53e3\u6eb6\u819c2022\u5e74\u5728\u533b\u9662\u7ec8\u7aef\u5e02\u573a\u7684\u9500\u552e\u89c4\u6a21\u4e3a2718.50\u4e07\u5143\uff0c\u540c\u6bd4\u589e\u957f751.92%\uff0c\u836f\u5e97\u7aef\u5219\u4e3a166.39\u4e07\u5143\uff0c\u540c\u6bd4\u589e\u957f329.85%\u3002<\/span><\/section>\n<\/section>\n<p>&nbsp;<\/p>\n<p><img decoding=\"async\" class=\"rich_pages wxw-img\" style=\"visibility: visible !important; width: 100%; height: auto; border-width: 1px; border-style: solid;\" title=\"Oral film formulations: A new frontier in high-end innovative preparations.\" src=\"https:\/\/www.abesmoke.com\/wp-content\/uploads\/2024\/11\/5-1730961154.webp\" alt=\"Oral film formulations: A new frontier in high-end innovative preparations.\" \/><\/p>\n<p>&nbsp;<\/p>\n<section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u6839\u636eMorder Intelligence\u62a5\u544a\u663e\u793a\uff0c\u53e3\u819c\u5236\u5242\u5e02\u573a\u89c4\u6a21\u9884\u8ba1\u52302024\u5e74\u4e3a30.1\u4ebf\u7f8e\u5143\uff0c\u9884\u8ba1\u52302029\u5e74\u5c06\u8fbe\u523047.5\u4ebf\u7f8e\u5143\uff0c\u5728\u9884\u6d4b\u671f\u5185\uff082024-2029\u5e74\uff09\u590d\u5408\u5e74\u589e\u957f\u7387\u4e3a9.56%\u3002\u5176\u4e2d\uff0c\u4e9a\u592a\u5730\u533a\u5e02\u573a\u589e\u957f\u901f\u5ea6\u6700\u5feb\u3002<\/span><\/section>\n<\/section>\n<p>&nbsp;<\/p>\n<p><img decoding=\"async\" class=\"rich_pages wxw-img\" style=\"visibility: visible !important; width: 100%; height: auto; border-width: 1px; border-style: solid;\" title=\"Oral film formulations: A new frontier in high-end innovative preparations.\" src=\"https:\/\/www.abesmoke.com\/wp-content\/uploads\/2024\/11\/9-1730961154.webp\" alt=\"Oral film formulations: A new frontier in high-end innovative preparations.\" \/><\/p>\n<p>&nbsp;<\/p>\n<\/section>\n<section title=\"\u4e09\u7ea7\u6807\u9898\">\n<section>\n<section>\n<section>\n<h3><span style=\"color: #0052ff;\"><strong><span style=\"font-size: 16px;\">\u56db\u3001\u53e3\u819c\u5236\u5242\uff1a\u521b\u65b0\u7684\u7a81\u7834\u53e3<\/span><\/strong><\/span><\/h3>\n<\/section>\n<section><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u76f8\u8f83\u4e8e\u836f\u7269\u5206\u5b50\u521b\u65b0\u6240\u9700\u7684\u5de8\u989d\u8d44\u91d1\u6295\u5165\u4e0e\u6f2b\u957f\u7814\u53d1\u5468\u671f\uff0c\u5242\u578b\u521b\u65b0\u5728\u6210\u672c\u6548\u76ca\u4e0a\u5c55\u73b0\u51fa\u663e\u8457\u4f18\u52bf\u3002\u636e\u5206\u6790\u62a5\u544a\u663e\u793a\uff0c\u65b0\u5242\u578b\u7814\u53d1\u6210\u672c\u8f83\u4f4e\uff0c\u4e14\u5468\u671f\u901a\u5e38\u4ec5\u4e3a\u65b0\u5316\u5408\u7269\u836f\u7269\u7684\u4e00\u534a\uff0c\u7ea6\u4e3a5\u5e74\u3002<\/span><span style=\"font-size: 16px;\">\u00a0<\/span><\/section>\n<section title=\"\">\n<section><img decoding=\"async\" class=\"rich_pages wxw-img\" style=\"word-break: break-word; line-height: 1.75; letter-spacing: 0.8px; writing-mode: horizontal-tb; flex-grow: 1; max-width: none !important; width: 100%; visibility: visible !important; height: auto; border-width: 1px; border-style: solid;\" title=\"Oral film formulations: A new frontier in high-end innovative preparations.\" src=\"https:\/\/www.abesmoke.com\/wp-content\/uploads\/2024\/11\/3-1730961155.webp\" alt=\"Oral film formulations: A new frontier in high-end innovative preparations.\" \/><\/section>\n<\/section>\n<section title=\"\"><span style=\"font-size: 12px;\">\u6570\u636e\u6765\u6e90\uff1a\u95fb\u6653\u5149et al.,<\/span><span style=\"font-size: 16px;\">\u00a0<\/span><\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u5c3d\u7ba1\u65b0\u5242\u578b\u4e0e\u65b0\u5316\u5408\u7269\u836f\u7269\u7684\u5e02\u573a\u76d1\u6d4b\u671f\u76f8\u8fd1\uff0c\u4f46\u5176\u4f9d\u6258\u4e8e\u73b0\u6709\u5316\u5408\u7269\u7684\u6539\u826f\uff0c\u51ed\u501f\u5236\u5242\u751f\u4ea7\u52a0\u5de5\u5de5\u827a\u7684\u6280\u672f\u95e8\u69db\uff0c\u4ecd\u80fd\u6784\u5efa\u5f3a\u5927\u7684\u5e02\u573a\u7ade\u4e89\u529b\u3002\u8fd9\u4e00\u95e8\u69db\u4e0d\u4ec5\u8d85\u8d8a\u4e86\u4e13\u5229\u4fdd\u62a4\u7684\u5c40\u9650\uff0c\u800c\u4e14\u901a\u8fc7\u4f18\u5316\u7ed9\u836f\u65b9\u5f0f\uff0c\u63d0\u5347\u836f\u7269\u54c1\u8d28\uff0c\u5ef6\u957f\u5e02\u573a\u751f\u547d\u5468\u671f\uff0c\u4f7f\u65b0\u578b\u5236\u5242\u5728\u5e02\u573a\u72ec\u5360\u671f\u5185\u7684\u8868\u73b0\u8db3\u4ee5\u5ab2\u7f8e\u5168\u65b0\u836f\u7269\u3002<\/span><span style=\"font-size: 16px;\">\u00a0<\/span><\/section>\n<section title=\"\"><span style=\"color: #0052ff;\"><strong><span style=\"font-size: 16px;\">\u4e94\u3001\u653f\u7b56\u652f\u6301\u4e0e\u5e02\u573a\u589e\u957f<\/span><\/strong><\/span><span style=\"font-size: 16px;\">\u00a0<\/span><\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">2021\u5e74\u5e95\u56fd\u5bb6\u53d1\u6539\u59d4\u8054\u5408\u79d1\u6280\u90e8\u3001\u5546\u52a1\u90e8\u548c\u56fd\u5bb6\u536b\u5065\u59d4\u7b499\u4e2a\u90e8\u5206\u8054\u5408\u5370\u53d1\u4e86\u300a\u5341\u56db\u4e94\u533b\u836f\u5de5\u4e1a\u53d1\u5c55\u89c4\u5212\u300b\uff0c\u5176\u4e2d\u76f4\u63a5\u5c06\u53e3\u6eb6\u819c\u4f5c\u4e3a\u4e86\u533b\u836f\u4ea7\u4e1a\u5316\u6280\u672f\u516c\u5173\u5de5\u7a0b\u4e4b\u4e00\uff0c\u8db3\u53ef\u4ee5\u770b\u51fa\u56fd\u5bb6\u5bf9\u53e3\u6eb6\u819c\u4ea7\u54c1\u7684\u653f\u7b56\u652f\u6301\u3002\u968f\u7740\u4eba\u53e3\u8001\u9f84\u5316\u4e0d\u65ad\u52a0\u5267\uff0c\u5bf9\u5b89\u5168\u65e0\u969c\u788d\u7ed9\u836f\u65b9\u5f0f\u7684\u9700\u6c42\u4f1a\u65e5\u76ca\u589e\u52a0\uff0c\u5e02\u573a\u76f4\u63a5\u63a8\u52a8OTF\u5e02\u573a\u7684\u589e\u957f\u3002<\/span><span style=\"font-size: 16px;\">\u00a0<\/span><\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u53e3\u6eb6\u819c\u6280\u672f\u4f5c\u4e3a\u533b\u836f\u884c\u4e1a\u7684\u521b\u65b0\u7a81\u7834\uff0c\u4e0d\u4ec5\u63d0\u4f9b\u4e86\u4e00\u79cd\u65b0\u7684\u7ed9\u836f\u65b9\u5f0f\uff0c\u8fd8\u4e3a\u836f\u7269\u7814\u53d1\u548c\u5e02\u573a\u5e26\u6765\u4e86\u65b0\u7684\u673a\u9047\u3002\u968f\u7740\u6280\u672f\u7684\u6210\u719f\u548c\u5e02\u573a\u7684\u6269\u5927\uff0c\u9884\u8ba1\u672a\u6765\u51e0\u5e74\u53e3\u6eb6\u819c\u5c06\u5728\u533b\u836f\u884c\u4e1a\u4e2d\u5360\u636e\u66f4\u52a0\u91cd\u8981\u7684\u5730\u4f4d\u3002<\/span><\/section>\n<section title=\"\u4e09\u7ea7\u6807\u9898\">\n<section>\n<section>\n<section><\/section>\n<section>\n<section>\n<section>\n<section>\n<h3><span style=\"font-size: 16px;\"><span style=\"font-size: 16px; color: #0052ff;\"><strong>\u516d\u3001\u53e3\u819c\u5236\u5242\u5f00\u53d1\u4e2d\u7684\u5173\u952e\u70b9\u00a0<\/strong><\/span><\/span><\/h3>\n<\/section>\n<section><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section title=\"\"><strong><span style=\"font-size: 16px;\">1\u3001\u00a0\u751f\u4ea7\u5de5\u827a<\/span><\/strong><span style=\"font-size: 16px;\">\u00a0<\/span><span style=\"font-size: 16px;\">\u81ea\u53e3\u8154\u8584\u819c\u5e94\u7528\u8bde\u751f\u4e4b\u65e5\u8d77\uff0c\u6eb6\u5242\u6d47\u94f8\u6cd5\u4fbf\u7a33\u5c45\u5176\u5236\u5907\u65b9\u6cd5\u7684\u5b9d\u5ea7\u3002\u8fd9\u79cd\u65b9\u6cd5\u4ee5\u5de5\u827a\u7b80\u5355\u3001\u6210\u672c\u4f4e\u5ec9\u8457\u79f0\uff0c\u6210\u4e3a\u5c06\u53e3\u8154\u8584\u819c\u7528\u4e8e\u4e34\u5e8a\u7684\u6700\u5b9e\u7528\u624b\u6bb5\u3002<\/span><span style=\"font-size: 16px;\">\u00a0<\/span><\/p>\n<p><span style=\"font-size: 16px;\">\u7136\u800c\uff0c\u968f\u7740\u79d1\u6280\u7684\u53d1\u5c55\uff0c\u65b0\u6280\u672f\u5982\u70ed\u7194\u6324\u51fa\u6cd5\u3001\u9759\u7535\u7eba\u4e1d\u6cd5\u548c\u6253\u5370\u6cd5\u7b49\u9010\u6e10\u5d2d\u9732\u5934\u89d2\uff0c\u5b83\u4eec\u4e0d\u4ec5\u5f25\u8865\u4e86\u6eb6\u5242\u6d47\u94f8\u6cd5\u7684\u4e0d\u8db3\uff0c\u8fd8\u8fdb\u4e00\u6b65\u63d0\u5347\u4e86\u53e3\u8154\u8584\u819c\u7684\u6027\u80fd\u3002<\/span><\/p>\n<p><span style=\"font-size: 16px;\">\u00a0<\/span><\/p>\n<\/section>\n<ul class=\"list-paddingleft-1\" style=\"list-style-type: circle;\">\n<li>\n<section title=\"\"><span style=\"font-size: 16px;\">\u6eb6\u5242\u6d47\u94f8\u6cd5<\/span><\/section>\n<\/li>\n<\/ul>\n<section title=\"\"><span style=\"font-size: 16px;\">\u6eb6\u5242\u6d47\u94f8\u6cd5(solvent casting)\u662f\u7ecf\u5178\u7684\u53e3\u8154\u8584\u819c\u5236\u5907\u65b9\u6cd5\u3002\u901a\u8fc7\u5c06\u6210\u819c\u6750\u6599\u3001\u6d3b\u6027\u6210\u5206\u548c\u5176\u4ed6\u8f85\u6599\u6eb6\u89e3\u6216\u5206\u6563\u4e8e\u6c34\u4e2d\uff0c\u7136\u540e\u6d47\u94f8\u6210\u819c\u3002\u8fd9\u79cd\u65b9\u6cd5\u5de5\u827a\u7b80\u5355\uff0c\u6210\u672c\u8f83\u4f4e\uff0c\u9002\u5408\u4e34\u5e8a\u4f7f\u7528\u3002<\/span><span style=\"font-size: 16px;\">\u00a0<\/span><span style=\"font-size: 16px;\">\u7136\u800c\u5b83\u4e5f\u6709\u7f3a\u70b9\uff0c\u6bd4\u5982\u4f7f\u7528\u5927\u91cf\u6709\u673a\u6eb6\u5242\u53ef\u80fd\u5bf9\u5065\u5eb7\u548c\u73af\u5883\u9020\u6210\u5f71\u54cd\uff0c\u4e14\u6709\u673a\u6eb6\u5242\u6b8b\u7559\u53ef\u80fd\u5bfc\u81f4\u819c\u7ed3\u6784\u4e0d\u826f\u53d8\u5316\uff0c\u5f71\u54cd\u836f\u7269\u6eb6\u51fa\u5ea6\u548c\u5b89\u5168\u6027\u3002<\/span><span style=\"font-size: 16px;\">\u00a0<\/span><\/p>\n<\/section>\n<section title=\"\">\n<section><img decoding=\"async\" class=\"rich_pages wxw-img\" style=\"word-break: break-word; line-height: 1.75; letter-spacing: 0.8px; writing-mode: horizontal-tb; flex-grow: 1; max-width: none !important; width: 100%; visibility: visible !important; height: auto; border-width: 1px; border-style: solid;\" title=\"Oral film formulations: A new frontier in high-end innovative preparations.\" src=\"https:\/\/www.abesmoke.com\/wp-content\/uploads\/2024\/11\/9-1730961155.webp\" alt=\"Oral film formulations: A new frontier in high-end innovative preparations.\" \/><\/section>\n<section><\/section>\n<\/section>\n<ul class=\"list-paddingleft-1\" style=\"list-style-type: circle;\">\n<li>\n<section title=\"\"><span style=\"font-size: 16px;\">\u70ed\u7194\u6324\u51fa\u6cd5<\/span><\/section>\n<\/li>\n<\/ul>\n<p><span style=\"font-size: 16px;\">\u70ed\u7194\u6324\u51fa\u6cd5\uff08Hot-melt Extrusion\uff09\u662f\u4e00\u79cd\u521b\u65b0\u7684\u53e3\u8154\u8584\u819c\u5236\u5907\u6280\u672f\u3002\u5b83\u5c06\u539f\u8f85\u6599\u6df7\u5408\u7269\u5728\u9ad8\u6e29\u4e0b\u7194\u878d\u540e\u6324\u51fa\u6210\u819c\uff0c\u907f\u514d\u4e86\u6709\u673a\u6eb6\u5242\u7684\u4f7f\u7528\uff0c\u5236\u9020\u8fc7\u7a0b\u5feb\u901f\uff0c\u65e0\u9700\u5e72\u71e5\uff0c\u542b\u91cf\u5747\u4e00\u5ea6\u9ad8\u3002<\/span><\/p>\n<p><span style=\"font-size: 16px;\">\u00a0<\/span><\/p>\n<p><span style=\"font-size: 16px;\">\u4f46\u662f\uff0c\u5b83\u8981\u6c42\u836f\u7269\u548c\u8f85\u6599\u80fd\u591f\u8010\u9ad8\u6e29\uff0c\u4e0d\u9002\u7528\u4e8e\u70ed\u654f\u611f\u836f\u7269\uff0c\u4e14\u8bbe\u5907\u590d\u6742\uff0c\u9700\u8981\u7cbe\u7ec6\u7684\u64cd\u4f5c\u63a7\u5236\u3002\u6b64\u5916\uff0c\u5b58\u5728\u4e00\u4e9b\u6311\u6218\uff0c\u4f8b\u5982\u6e29\u5ea6\u964d\u4f4e\u65f6API\u53ef\u80fd\u91cd\u7ed3\u6676\uff0c\u8fd9\u53ef\u4ee5\u901a\u8fc7\u589e\u52a0\u9ad8\u7c98\u5ea6\u805a\u5408\u7269\u6216\u589e\u5851\u5242\u6765\u89e3\u51b3\u3002\u8fd8\u6709\u4e00\u79cd\u95ee\u9898\u662f\u79bb\u6a21\u81a8\u80c0\u73b0\u8c61\uff0c\u53ef\u4ee5\u901a\u8fc7\u964d\u4f4e\u87ba\u65cb\u6746\u901f\u5ea6\u6765\u51cf\u5c11\u3002<\/span><\/p>\n<p><span style=\"font-size: 16px;\">\u00a0<\/span><\/p>\n<section title=\"\">\n<section><img decoding=\"async\" class=\"rich_pages wxw-img\" style=\"word-break: break-word; line-height: 1.75; letter-spacing: 0.8px; writing-mode: horizontal-tb; flex-grow: 1; max-width: none !important; width: 100%; visibility: visible !important; height: auto; border-width: 1px; border-style: solid;\" title=\"Oral film formulations: A new frontier in high-end innovative preparations.\" src=\"https:\/\/www.abesmoke.com\/wp-content\/uploads\/2024\/11\/5-1730961155.webp\" alt=\"Oral film formulations: A new frontier in high-end innovative preparations.\" \/><\/section>\n<\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u00a0<\/span><\/p>\n<ul class=\"list-paddingleft-1\" style=\"list-style-type: circle;\">\n<li><span style=\"font-size: 16px;\">\u9759\u7535\u7eba\u4e1d\u6cd5<\/span><\/li>\n<\/ul>\n<p><span style=\"font-size: 16px;\">\u9759\u7535\u7eba\u4e1d\u6cd5\uff08Electrospinning\uff09\u53ef\u4ee5\u5236\u5907\u7eb3\u7c73\u7ea7\u522b\u7684\u7ea4\u7ef4\u4e1d\u3002\u7531\u4e8e\u5176\u6bd4\u8868\u9762\u79ef\u5927\uff0c\u53ef\u4ee5\u63d0\u9ad8\u8f7d\u836f\u91cf\uff0c\u5e76\u589e\u5f3a\u836f\u7269\u7684\u6eb6\u89e3\u5ea6\u548c\u6e17\u900f\u6027\u3002\u6b64\u6cd5\u5236\u5907\u7684\u53e3\u8154\u8584\u819c\u5177\u5907\u4f18\u826f\u7684\u673a\u68b0\u5f3a\u5ea6\u548c\u67d4\u97e7\u6027\uff0c\u53ef\u4ee5\u5b9e\u73b0\u836f\u7269\u7684\u63a7\u91ca\u3002<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><strong><span style=\"font-size: 16px;\">2\u3001\u8d28\u91cf\u63a7\u5236<\/span><\/strong><\/p>\n<section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u00a0<\/span><\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u8d28\u91cf\u63a7\u5236\u7814\u7a76\u5e94\u7ed3\u5408\u53e3\u8154\u819c\u5242\u7684\u5236\u5242\u7279\u6027\u548c\u4ea7\u54c1\u7279\u6027\u6765\u786e\u5b9a\u3002\u5173\u6ce8\u7684\u6307\u6807\u5305\u62ec\u4f46\u4e0d\u9650\u4e8e\u673a\u68b0\u6027\u80fd\uff08\u5982\u8010\u6298\u6027\u3001\u65ad\u88c2\u5f3a\u5ea6\u3001\u6297\u62c9\u5f3a\u5ea6\u7b49\uff09\u548c\u751f\u7269\u5b66\u7279\u6027\uff08\u5982\u5d29\u89e3\/\u6eb6\u5316\u65f6\u95f4\u3001\u6eb6\u51fa\u5ea6\u3001\u523a\u6fc0\u6027\u3001\u9ecf\u9644\u6027\uff09\u3002\u4e00\u4e9b\u6307\u6807\u53ef\u80fd\u672a\u88ab\u7eb3\u5165\u6ce8\u518c\u6807\u51c6\uff0c\u800c\u662f\u4f5c\u4e3a\u653e\u884c\u6807\u51c6\u7684\u4e00\u90e8\u5206\u3002<\/span><\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u00a0<\/span><\/section>\n<\/section>\n<section>\n<section title=\"\"><span style=\"font-size: 16px;\">2010\u5e74\uff0cFDA\u6279\u51c6\u4e86\u6602\u4e39\u53f8\u743c\u53e3\u6eb6\u819c\uff08ZUPLENZ\u00ae\uff09\u4e0a\u5e02\u3002\u6839\u636e\u5176FDA\u836f\u5b66\u5ba1\u8bc4\u62a5\u544a\uff0c\u8d28\u91cf\u6807\u51c6\u6db5\u76d6\u4e86\u6027\u72b6\u3001\u9274\u522b\u3001\u542b\u91cf\u3001\u6709\u5173\u7269\u8d28\u3001\u6eb6\u51fa\u5ea6\u3001\u542b\u91cf\u5747\u5300\u5ea6\u548c\u5fae\u751f\u7269\u9650\u5ea6\u7b49\u65b9\u9762\u3002\u4e0e\u5927\u591a\u6570\u666e\u901a\u7247\u5242\u76f8\u6bd4\uff0cZUPLENZ\u00ae\u7684\u6eb6\u51fa\u901f\u5ea6\u8f83\u5feb\uff0c\u80fd\u57284\u81f321\u79d2\u5185\u5b8c\u5168\u6eb6\u89e3\u4e8e\u820c\u4e0a\u3002<\/span><\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u00a0<\/span><\/section>\n<\/section>\n<section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u53e3\u8154\u819c\u5242\u65e0\u9700\u6db2\u4f53\u8f85\u52a9\u5373\u53ef\u5feb\u901f\u6eb6\u89e3\uff0c \u56e0\u6b64\uff0c\u6eb6\u51fa\u5ea6\u548c\u6eb6\u5316\u65f6\u95f4\uff08\u5d29\u89e3\u65f6\u95f4\uff09\u662f\u5173\u952e\u7684\u8d28\u91cf\u63a7\u5236\u6307\u6807\u3002\u5728\u8fdb\u884c\u6eb6\u51fa\u5ea6\u63a7\u5236\u65f6\uff0c\u5e94\u8003\u8651\u6eb6\u51fa\u88c5\u7f6e\u7684\u9009\u62e9\u548c\u6eb6\u51fa\u9650\u5ea6\u7684\u8bbe\u5b9a\u3002<\/span><\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u00a0<\/span><\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u4f53\u5916\u7814\u7a76\u4e2d\uff0c\u901a\u8fc7\u6bd4\u8f83\u53c2\u6bd4\u5236\u5242\u4e0e\u81ea\u5236\u6837\u54c1\u7684\u6eb6\u51fa\u76f8\u4f3c\u6027\uff0c\u53ef\u4ee5\u5728\u4e00\u5b9a\u7a0b\u5ea6\u4e0a\u964d\u4f4e\u4f53\u5185\u751f\u7269\u4e0d\u7b49\u6548\u7684\u98ce\u9669\u3002\u6eb6\u51fa\u5ea6\u7814\u7a76\u901a\u5e38\u7ed3\u5408\u836f\u7269\u7279\u6027\u3001\u4ea7\u54c1\u8bbe\u8ba1\uff0c\u5e76\u53c2\u8003FDA\u6eb6\u51fa\u5ea6\u6570\u636e\u5e93\u7b49\u8d44\u6e90\uff0c\u4ee5\u9009\u62e9\u5408\u9002\u7684\u6eb6\u51fa\u88c5\u7f6e\u548c\u65b9\u6cd5\uff08\u6eb6\u51fa\u4ecb\u8d28\u3001\u8f6c\u901f\u3001\u53d6\u6837\u70b9\u7b49\uff09\u3002<\/span><\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u00a0<\/span><\/section>\n<\/section>\n<section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u76ee\u524d\uff0c\u5c1a\u65e0\u7edf\u4e00\u516c\u8ba4\u7684\u53e3\u8154\u819c\u5242\u6eb6\u51fa\u65b9\u6cd5\u3002\u88684\u5217\u51fa\u4e86FDA\u548c\u65e5\u672c\u4e0a\u5e02\u7684\u90e8\u5206\u53e3\u8154\u819c\u5242\u7684\u6eb6\u51fa\u5ea6\u8bd5\u9a8c\u65b9\u6cd5\uff0c\u5e38\u89c1\u7684\u5305\u62ec\u6868\u6cd5\u3001\u7bee\u6cd5\u3001\u6868\u789f\u6cd5\u548c\u6d41\u901a\u6c60\u6cd5\u7b49\u3002<\/span><\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u00a0<\/span><\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u7531\u4e8e\u53e3\u8154\u819c\u5242\u5bb9\u6613\u6f02\u6d6e\uff0c\u6709\u65f6\u4f1a\u589e\u52a0\u6c89\u964d\u7bee\u88c5\u7f6e\uff0c\u4f8b\u5982\u65e5\u672c\u4e0a\u5e02\u7684\u6602\u4e39\u53f8\u743c\u53e3\u6eb6\u819c\uff08OD Film\uff09\u91c7\u7528\u4e86\u6868\u6cd5\u52a0\u6c89\u964d\u7bee\u88c5\u7f6e\uff1b\u800c\u7f8e\u56fd\u4e0a\u5e02\u7684\u6602\u4e39\u53f8\u743c\u53e3\u6eb6\u819c\uff08ZUPLENZ\u00ae\uff09\u5219\u91c7\u7528\u4e86\u6868\u789f\u6cd5\uff08\u914d\u4e0d\u9508\u94a2\u7f51\u789f\uff09\u3002<\/span><\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u00a0<\/span><\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u6eb6\u5316\u65f6\u95f4\u662f\u7279\u522b\u5173\u6ce8\u7684\u6307\u6807\uff0c\u5176\u6d4b\u5b9a\u65b9\u6cd5\u5e94\u6a21\u62df\u4e34\u5e8a\u5b9e\u9645\u4f7f\u7528\u60c5\u51b5\uff0c\u5e76\u63d0\u4f9b\u79d1\u5b66\u7684\u9650\u5ea6\u3002\u4e0d\u540c\u65b9\u6cd5\u95f4\u7684\u5bf9\u6bd4\u7814\u7a76\u6709\u65f6\u53ef\u4ee5\u63d0\u4f9b\u66f4\u5145\u5206\u7684\u4f9d\u636e\u3002<\/span><\/section>\n<section title=\"\"><span style=\"font-size: 16px;\">\u00a0<\/span><\/section>\n<\/section>\n<section title=\"\">\n<section>\n<section><img decoding=\"async\" class=\"rich_pages wxw-img\" style=\"width: 100%; visibility: visible !important; height: auto; border-width: 1px; border-style: solid;\" title=\"Oral film formulations: A new frontier in high-end innovative preparations.\" src=\"https:\/\/www.abesmoke.com\/wp-content\/uploads\/2024\/11\/0-1730961156.webp\" alt=\"Oral film formulations: A new frontier in high-end innovative preparations.\" \/><span style=\"font-size: 16px;\">\u00a0<\/span><span style=\"font-size: 16px;\">\u65e5\u672c\u4e0a\u5e02\u7684\u591a\u5948\u54cc\u9f50\u53e3\u6eb6\u819c\u7684\u6eb6\u51fa\u5ea6\u5b9e\u9a8c\u91c7\u7528\u4e86\u6868\u6cd5\u88c5\u7f6e\uff0c\u00a0\u6eb6\u51fa\u4ecb\u8d28\u4f53\u79ef\u4e3a900mL\u3002\u81ea\u5236\u6837\u54c1\u57284\u79cd\u4ecb\u8d28\uff08pH=1.2\u3001pH=4.0\u3001pH=6.8\u548c\u6c34\uff09\u4e2d\uff0c\u4ee550r\/min\u7684\u8f6c\u901f\u4e0e\u53c2\u6bd4\u5236\u5242\u8fdb\u884c\u4f53\u5916\u6eb6\u51fa\u5b9e\u9a8c\u5bf9\u6bd4\uff1b\u5e76\u5728\u7279\u5b9a\u4ecb\u8d28pH=6.8\u4e2d\uff0c\u4ee5100r\/min\u7684\u8f6c\u901f\u8fdb\u884c\u8fdb\u4e00\u6b65\u5bf9\u6bd4\u3002<\/span><span style=\"font-size: 16px;\">\u00a0<\/span><\/p>\n<p><span style=\"font-size: 16px;\">\u7ed3\u679c\u663e\u793a\uff0c3mg\u89c4\u683c\u5728pH=4.0\u548c\u6c34\u4e2d\u4e0e\u53c2\u6bd4\u5236\u5242\u7684\u6eb6\u51fa\u884c\u4e3a\u4e0d\u76f8\u4f3c\uff0c\u800c5mg\u548c10mg\u89c4\u683c\u5728\u4ecb\u8d28\u6c34\u4e2d\u4e0e\u53c2\u6bd4\u5236\u5242\u7684\u6eb6\u51fa\u884c\u4e3a\u4e0d\u76f8\u4f3c\uff0c\u5176\u4ed6\u4ecb\u8d28\u4e2d\u6eb6\u51fa\u884c\u4e3a\u76f8\u4f3c\u3002\u7531\u4e8e\u836f\u7269\u5728\u4f53\u5185\u7684\u884c\u4e3a\u590d\u6742\uff0c\u4f53\u5916\u6eb6\u51fa\u65b9\u6cd5\u5b58\u5728\u5c40\u9650\u6027\uff0c\u4f53\u5916\u6eb6\u51fa\u53ef\u80fd\u4ec5\u5728\u4e00\u5b9a\u7a0b\u5ea6\u4e0a\u9884\u6d4b\u4f53\u5185\u884c\u4e3a\u3002<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-size: 16px;\">\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\uff0c\u91c7\u7528\u4e0e\u6c34\u540c\u670d\u548c\u4e0d\u4e0e\u6c34\u540c\u670d\u7684\u7a7a\u8179\u751f\u7269\u7b49\u6548\u6027\u8bd5\u9a8c\uff0c\u4e24\u8005\u5747\u663e\u793a\u819c\u5242\u4e0e\u7247\u5242\u751f\u7269\u7b49\u6548\uff0c\u8868\u660e\u6c34\u4ecb\u8d28\u53ef\u80fd\u5e76\u4e0d\u80fd\u5f88\u597d\u5730\u9884\u6d4b\u4f53\u5185\u7ed3\u679c\u3002<\/span><\/p>\n<p><span style=\"font-size: 16px;\">\u00a0<\/span><\/p>\n<p><span style=\"font-size: 14px;\">\u6765\u6e90\uff1a\u65b0\u9633\u552f\u5eb7<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"letter-spacing: 0.578px;\">\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<blockquote class=\"keep-source\"><p>\u539f\u6587\u59cb\u53d1\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\uff08\u96fe\u5316\u79d1\u6280\u5c55\uff09\uff1a<a href=\"http:\/\/mp.weixin.qq.com\/s\/Gu871zd52rLAavS1gkxYEQ\" target=\"_blank\" rel=\"noopener\">Oral film formulations: A new frontier in high-end innovative preparations.<\/a><\/p><\/blockquote>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>\u5728\u533b\u7597\u5065\u5eb7\u7684\u5e7f\u9614\u821e\u53f0\u4e0a\uff0c\u6bcf\u4e00\u6b21\u6280\u672f\u7684\u9769\u65b0\u90fd\u4f34\u968f\u7740\u5bf9\u4eba\u7c7b\u798f\u7949\u7684\u6df1\u523b\u5173\u6000\u3002 \u4f20\u7edf\u7684\u836f\u7269\u7ed9\u836f\u65b9\u5f0f\uff0c\u5c3d\u7ba1\u5386\u7ecf\u5c81\u6708\u8003\u9a8c\uff0c\u4f46\u5728\u73b0\u4ee3\u793e\u4f1a\u5374\u9010\u6e10\u663e\u9732\u51fa\u5176\u5c40\u9650\u6027\uff1a\u541e\u54bd\u56f0\u96be\u7684\u60a3\u8005\u9762\u5bf9\u80f6\u56ca\u4e0e\u7247\u5242\u65f6\u7684\u65e0\u5948\uff0c\u513f\u7ae5\u4e0e\u8001\u5e74 &hellip;<\/p>","protected":false},"author":2,"featured_media":47069,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false},"version":2}},"categories":[1],"tags":[],"class_list":["post-47068","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"jetpack_publicize_connections":[],"_links":{"self":[{"href":"https:\/\/www.abesmoke.com\/en\/wp-json\/wp\/v2\/posts\/47068","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.abesmoke.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.abesmoke.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.abesmoke.com\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.abesmoke.com\/en\/wp-json\/wp\/v2\/comments?post=47068"}],"version-history":[{"count":0,"href":"https:\/\/www.abesmoke.com\/en\/wp-json\/wp\/v2\/posts\/47068\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.abesmoke.com\/en\/wp-json\/wp\/v2\/media\/47069"}],"wp:attachment":[{"href":"https:\/\/www.abesmoke.com\/en\/wp-json\/wp\/v2\/media?parent=47068"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.abesmoke.com\/en\/wp-json\/wp\/v2\/categories?post=47068"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.abesmoke.com\/en\/wp-json\/wp\/v2\/tags?post=47068"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}