{"id":33057,"date":"2022-04-26T12:02:06","date_gmt":"2022-04-26T04:02:06","guid":{"rendered":"https:\/\/www.abesmoke.com\/?p=33057"},"modified":"2022-04-26T12:02:48","modified_gmt":"2022-04-26T04:02:48","slug":"ca73abf1c2","status":"publish","type":"post","link":"https:\/\/www.abesmoke.com\/en\/a\/33057","title":{"rendered":"\u82f1\u56fd\u7535\u5b50\u70df\u8c03\u5473\u7269\u8d28\u6bd2\u7406\u5b66\u8bc4\u4f30\u6846\u67b6\u6307\u5357\u7b80\u4ecb"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<section style=\"margin-top: 10px; margin-bottom: 10px; white-space: normal; color: #3f3f3f; font-family: Optima-Regular, PingFangTC-light; font-size: 14px; letter-spacing: 1px; text-align: center; justify-content: center; box-sizing: border-box;\">\n<section style=\"display: inline-block; width: auto; vertical-align: top; min-width: 10%; max-width: 100%; height: auto; border-bottom: 1px solid #315ea3; border-bottom-right-radius: 0px; line-height: 0; box-sizing: border-box;\">\n<section 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style=\"letter-spacing: normal; background-color: #d6d6d6;\">\u6b65\u9aa45\uff1a<\/span><span style=\"letter-spacing: normal;\">\u8bc4\u4f30\u901a\u8fc7\u7535\u5b50\u70df\u4f7f\u7528\u4ea7\u751f\u7684\u63a5\u89e6\u6c34\u5e73\u662f\u5426\u9ad8\u4e8e\u70f9\u996a\u4f7f\u7528\u4ea7\u751f\u7684\u63a5\u89e6\u6c34\u5e73\u3002\u5982\u679c\u63a5\u89e6\u91cf\u4e0e\u70f9\u996a\u65f6\u7684\u63a5\u89e6\u91cf\u76f8\u4f3c\u6216\u4f4e\u4e8e\u70f9\u996a\u65f6\u7684\u63a5\u89e6\u91cf\uff0c\u5219\u8be5\u8c03\u5473\u5316\u5408\u7269\u9884\u8ba1\u4e0d\u4f1a\u5bf9\u5065\u5eb7\u9020\u6210\u5f71\u54cd\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<section style=\"width: 60px; margin-top: -65px; margin-left: auto;\"><\/section>\n<\/section>\n<\/section>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<section>\n<section style=\"text-align: left; margin-top: 10px; margin-bottom: 10px;\">\n<section style=\"background-color: #a0b8ff; display: inline-block; margin-left: 20px;\">\n<section style=\"font-size: 16px; letter-spacing: 2px; padding-right: 8px; padding-left: 8px; box-sizing: border-box;\"><span style=\"color: #ffffff;\"><strong>\u6bcf\u6b65\u9aa4\u5b8c\u6210\u65f6\u8f93\u51fa\u7ed3\u679c<\/strong><\/span><\/p>\n<\/section>\n<\/section>\n<section style=\"margin-top: -12px; box-sizing: border-box; border: 1px solid #a0b8ff;\">\n<section style=\"margin: 15px; color: #323232; letter-spacing: 2px; font-size: 14px; line-height: 1.75em; text-align: justify; transform: rotateZ(0deg); -webkit-transform: rotateZ(0deg); -moz-transform: rotateZ(0deg); -ms-transform: rotateZ(0deg); -o-transform: rotateZ(0deg);\"><span style=\"background-color: #d6d6d6;\">\u6b65\u9aa41\uff1a<\/span>\u5982\u679c\u8c03\u5473\u5316\u5408\u7269\u3001\u964d\u89e3\u548c\/\u6216\u53cd\u5e94\u4ea7\u7269\u4e0e\u70f9\u996a\u8fc7\u7a0b\u4e2d\u4ea7\u751f\u7684\u4e0d\u540c\uff0c\u4e14\u6ca1\u6709\u8db3\u591f\u7684\u4fe1\u606f\u5e94\u7528\u98ce\u9669\u8bc4\u4f30\u6846\u67b6\uff0c\u5219\u5e94\u4f7f\u7528TTC\u65b9\u6cd5\u8fdb\u884c\u8bc4\u4f30\uff0c\u5e76\u6839\u636e\u53e3\u670d\u503c\u8fdb\u884c\u8def\u7ebf\u95f4\u63a8\u65ad\u3002TTC\u5e94\u4f5c\u4e3a\u7535\u5b50\u70df\u6db2\u4f53\u4e2d\u9999\u6599\u4f7f\u7528\u7684\u8bc1\u636e\u6743\u91cd\u8bc4\u4f30\u7684\u4e00\u90e8\u5206\u3002\u5e94\u8bc4\u4f30\u90a3\u4e9b\u8d85\u8fc7\u5176\u9002\u5f53TTC\u503c\u7684\u5316\u5408\u7269\u5728\u7535\u5b50\u70df\u6db2\u4f53\u4e2d\u7684\u9002\u7528\u6027\uff0c\u4e0d\u8d85\u8fc7TTC\u503c\u7684\u4e0d\u4f1a\u5f15\u8d77\u5065\u5eb7\u95ee\u9898\u3002\u5728\u6846\u67b6\u7684\u7b2c4\u6b65\u4e2d\uff0c\u5e94\u8bc4\u4f30\u4e0e\u70f9\u996a\u4f7f\u7528\u4ea7\u751f\u7684\u8c03\u5473\u5316\u5408\u7269\u3001\u964d\u89e3\u548c\/\u6216\u53cd\u5e94\u4ea7\u7269\u6ca1\u6709\u5dee\u5f02\u7684\u8c03\u5473\u5316\u5408\u7269\u3001\u964d\u89e3\u548c\/\u6216\u53cd\u5e94\u4ea7\u7269\u5728\u901a\u8fc7\u53e3\u670d\u6216\u5438\u5165\u66b4\u9732\u4ea7\u751f\u7684\u7cfb\u7edf\u6bd2\u6027\u65b9\u9762\u7684\u76f8\u4f3c\u6027\u6216\u5dee\u5f02\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"background-color: #d6d6d6;\">\u6b65\u9aa42\uff1a<\/span>\u5e94\u8bc4\u4f30\u5177\u6709CMR\u6216\u6025\u6027\u6bd2\u6027(1\u7c7b\u62162\u7c7b)\u6216\u76ae\u80a4\u654f\u611f\u6027(1\u7c7b)\u534f\u8c03\u6b27\u6d32\u5206\u7c7b\u7684\u8c03\u5473\u5316\u5408\u7269\u662f\u5426\u9002\u5408\u5728\u7535\u5b50\u70df\u6db2\u4e2d\u4f7f\u7528\u3002\u5e94\u8003\u8651\u5f71\u54cd\u7684\u4e25\u91cd\u7a0b\u5ea6\u548c\u53d1\u751f\u7387\u3002\u5e94\u8fdb\u884c\u98ce\u9669\u8bc4\u4f30\uff0c\u53ef\u80fd\u4f7f\u7528\u66b4\u9732\u9650\u503c(MOE)\u65b9\u6cd5\u3002\u6839\u636e\u4f5c\u7528\u673a\u7406(MOA)\u548c\u5176\u4ed6\u76f8\u5173\u6bd2\u7406\u5b66\u4fe1\u606f\uff0c\u5982\u679cIARC\u5c06\u8c03\u5473\u5316\u5408\u7269\u5f52\u7c7b\u4e3a\u81f4\u764c\u7269\u8d28\uff0c\u5219\u8fd8\u5e94\u8003\u8651\u5176\u5728\u7535\u5b50\u70df\u6db2\u4e2d\u7684\u9002\u7528\u6027\u3002\u5982\u679c\u4e0a\u8ff0\u5176\u4ed6\u6570\u636e\u6765\u6e90\u6216\u57fa\u4e8e\u8bc1\u636e\u6743\u91cd\u548c\u4e13\u5bb6\u5224\u65ad\u7684\u5176\u4ed6\u53ef\u7528\u8bc1\u636e\u8868\u660e\u8c03\u5473\u5316\u5408\u7269\u53ef\u80fd\u4ea7\u751fCMR\u3001\u6025\u6027\u6bd2\u6027\u6216\u76ae\u80a4\u8fc7\u654f\uff0c\u5219\u5e94\u8003\u8651\u5bf9\u5316\u5408\u7269\u8fdb\u884c\u98ce\u9669\u8bc4\u4f30\u3002\u5982\u679c\u8c03\u5473\u5316\u5408\u7269\u672a\u88ab\u5f52\u7c7b\u4e3aCMR\u3001\u6025\u6027\u6bd2\u7d20\u6216\u76ae\u80a4\u8fc7\u654f\u5242\uff0c\u5219\u5e94\u8003\u8651\u5bf9\u80ba\u90e8\u7684\u5c40\u90e8\u5f71\u54cd(\u6b65\u9aa43)\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"background-color: #d6d6d6;\">\u6b65\u9aa43\uff1a<\/span>\u5bf9\u4e8e\u76ae\u80a4\u6216\u547c\u5438\u654f\u611f\u6027\u3001\u547c\u5438\u523a\u6fc0\u6027\u6216\u4ee5\u80ba\u4e3a\u9776\u5668\u5b98\u7684STOT 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style=\"background-color: #d6d6d6;\">\u6b65\u9aa44\uff1a<\/span>\u91cd\u590d\u5242\u91cf\u6bd2\u6027\u6f5c\u529b\u5e94\u4e0e\u5176\u4ed6\u7ec8\u70b9\u7684\u6570\u636e\u4e00\u8d77\u7528\u4e8e\u8bc1\u636e\u6743\u91cd\u5224\u65ad\u3002\u5982\u679c\u98df\u7528\u8c03\u5473\u5316\u5408\u7269\u901a\u8fc7\u5438\u5165\u4e0e\u6444\u5165\u4ea7\u751f\u4e0d\u540c\u7684\u6bd2\u6027\uff0c\u5e94\u8003\u8651\u5f71\u54cd\u7684\u4e25\u91cd\u7a0b\u5ea6\u548c\u53d1\u751f\u7387\u3002\u5e94\u8fdb\u884c\u98ce\u9669\u8bc4\u4f30\uff0c\u53ef\u80fd\u4f7f\u7528MOE\u65b9\u6cd5\u3002\u5982\u679c\u98df\u7528\u8c03\u5473\u5316\u5408\u7269\u901a\u8fc7\u5438\u5165\u4ea7\u751f\u7684\u6bd2\u6027\u4e0e\u6444\u5165\u7684\u6bd2\u6027\u76f8\u4f3c\uff0c\u5219\u5e94\u5728\u7b2c5\u6b65\u8003\u8651\u901a\u8fc7\u4f7f\u7528\u7535\u5b50\u70df\u4ea7\u751f\u7684\u66b4\u9732\u6c34\u5e73\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"background-color: #d6d6d6;\">\u6b65\u9aa45\uff1a<\/span>\u5982\u679c\u4f7f\u7528\u7535\u5b50\u70df\u7684\u66b4\u9732\u6c34\u5e73\u9ad8\u4e8e\u70f9\u996a\u4f7f\u7528\u7684\u66b4\u9732\u6c34\u5e73\uff0c\u5219\u5e94\u5c06\u66b4\u9732\u6c34\u5e73\u4e0e\u76f8\u5173\u5065\u5eb7\u6307\u5bfc\u503c(HBGV)\u6216TTC\u503c\u8fdb\u884c\u6bd4\u8f83\u3002\u5e94\u8bc4\u4f30\u90a3\u4e9b\u8d85\u8fc7\u5176\u9002\u5f53HBGV\/TTC\u503c\u7684\u5316\u5408\u7269\u5728\u7535\u5b50\u70df\u6db2\u4f53\u4e2d\u7684\u9002\u7528\u6027\u3002\u90a3\u4e9b\u4e0d\u8d85\u8fc7HBGV\/TTC\u503c\u7684\u75c5\u6bd2\u4e0d\u4f1a\u5f15\u8d77\u5065\u5eb7\u95ee\u9898\u3002\u5982\u679c\u901a\u8fc7\u7535\u5b50\u70df\u4f7f\u7528\u7684\u66b4\u9732\u6c34\u5e73\u4e0e\u70f9\u996a\u4f7f\u7528\u7684\u66b4\u9732\u6c34\u5e73\u76f8\u4f3c\u6216\u66f4\u4f4e\uff0c\u5219\u8be5\u8c03\u5473\u5316\u5408\u7269\u9884\u8ba1\u4e0d\u4f1a\u5bf9\u4f7f\u7528\u8005\u9020\u6210\u5065\u5eb7\u95ee\u9898\u3002\u5bf9\u65c1\u89c2\u8005\u98ce\u9669\u7684\u8bc4\u4f30\u9700\u8981\u5bf9\u63a5\u89e6\u60c5\u51b5\u8fdb\u884c\u9002\u5f53\u7684\u4f30\u8ba1\uff0c\u4ee5\u4fbf\u4e0eHBGV\/TTC\u8fdb\u884c\u6bd4\u8f83\u3002<\/p>\n<\/section>\n<\/section>\n<section style=\"width: 60px; margin-top: -65px; margin-left: auto;\"><\/section>\n<\/section>\n<\/section>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<section>\n<section style=\"text-align: left; margin-top: 10px; margin-bottom: 10px;\">\n<section style=\"background-color: #a0b8ff; display: inline-block; margin-left: 20px;\">\n<section style=\"font-size: 16px; letter-spacing: 2px; padding-right: 8px; padding-left: 8px; box-sizing: border-box;\"><span style=\"color: #ffffff;\"><strong>\u6570\u636e\u83b7\u53d6\u6765\u6e90<\/strong><\/span><\/p>\n<\/section>\n<\/section>\n<section style=\"margin-top: -12px; box-sizing: border-box; border: 1px solid #a0b8ff;\">\n<section style=\"margin: 15px; color: #323232; letter-spacing: 2px; font-size: 14px; line-height: 1.75em; text-align: justify; transform: rotateZ(0deg); -webkit-transform: rotateZ(0deg); -moz-transform: rotateZ(0deg); -ms-transform: rotateZ(0deg); -o-transform: rotateZ(0deg);\">\u6846\u67b6\u4e2d\u5305\u62ec\u4e86\u4e00\u4e9b\u6bd2\u7406\u5b66\u6570\u636e\u83b7\u53d6\u6765\u6e90\uff0c\u5305\u62ec\u6743\u5a01\u673a\u6784(\u5982IARC\u3001\u6b27\u76df\u7edf\u4e00\u5206\u7c7b)\u7684\u8bc4\u4f30\u6216\u5217\u5165SVHC\u5019\u9009\u540d\u5355\u7684\u7269\u8d28\uff0c\u975e\u52a8\u7269\u6570\u636e\u4e5f\u53ef\u7528\u4e8eQSAR\u5efa\u6a21\u548cTTC\u65b9\u6cd5\u3002<\/p>\n<\/section>\n<\/section>\n<section style=\"width: 60px; margin-top: -65px; margin-left: auto;\"><\/section>\n<\/section>\n<\/section>\n<p>&nbsp;<\/p>\n<section style=\"white-space: normal;\">\n<section>\n<section>\n<section>\n<section>\n<section style=\"margin: 10px 0px; text-align: justify; line-height: normal;\">\n<section style=\"padding-right: 4px; padding-left: 4px; display: inline-block; background-color: #fefefe; box-sizing: border-box;\">\n<section style=\"color: #fff7ef; font-size: 26px;\"><span style=\"font-size: 14px; font-family: \u5fae\u8f6f\u96c5\u9ed1; color: 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